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In subgroup analysis of the types of hospice as classified
2019-06-10

In subgroup analysis of the types of hospice as classified by the administrative authorities (Table 3), there was a trend that the patients admitted to a public hospital had a higher rate of dying in a hospice than those admitted to a private hospital, especially in the military and veterans\' hospi
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br Discussion Intriguingly in a case
2019-06-10

Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite differ
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br Disclosures br Acknowledgments br
2019-06-10

Disclosures Acknowledgments Introduction Long-term endurance sports have recently been recognized as one of the risk factors for atrial fibrillation (AF) [1–8]; widely accepted risk factors for AF include age, hypertension, diabetes mellitus, structural mu receptor antagonist disease, hyper
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In recent years there has been growing
2019-06-06

In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mR
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Therefore it is necessary to identify the
2019-06-06

Therefore, it is necessary to identify the accuracy of ECG in predicting a spontaneous syncope. Some waterproof Holter ECGs are commercially available; however, their use is not yet widespread. Moreover, patients may not experience syncope symptoms during the recording period. Given that the ILR can
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br Conclusions br Study limitations br Conflict
2019-06-06

Conclusions Study limitations Conflict of interest Introduction Dabigatran etexilate, an orally administered pro-drug, is rapidly converted by a serum esterase to dabigatran, a potent, direct, and competitive inhibitor of thrombin. It has an absolute bioavailability of 6.5% and a serum g
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Pharmacokinetics analysis of AT on SCID
2019-06-06

Pharmacokinetics analysis of AT-406 on SCID mice bearing MDA-MB-231 tumors has shown that AT-406 achieves a maximum concentration in plasma between 1.5μM and 9.9μM, and a maximum concentration in tumor tissue between 0.5μM and 18.2μM, depending on the dose and administration route (intravenous versu
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Introduction Acute erythroleukemia AEL is a rare subtype
2019-06-06

Introduction Acute erythroleukemia (AEL) is a rare subtype of acute myeloid leukemia (AML), accounting for 3–5% of all AML cases. It is characterized by the expansion of erythroblasts in the bone marrow (BM). Its clinical presentation often resembles myelodysplastic syndromes (MDS), both in terms o
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Upon diagnosis the patient s lymphoma and
2019-06-06

Upon diagnosis, the patient׳s lymphoma and HLH represented a therapeutic dilemma. Effective early therapy reduces mortality of HLH from 95% to 30–35% [4]. The HLH-2004 treatment protocol consists of T-cell targeted immunosupression with dexamethasone and cyclosporine, macrophage targeted etoposide w
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years ago published a groundbreaking and taboo breaking Seri
2019-06-06

5 years ago, published a groundbreaking (and taboo-breaking) Series on stillbirths. Its powerful mix of advocacy and hard data attracted more media attention than perhaps any other Series, and made waves on numerous levels, from the individual to the intergovernmental. Working closely with countrie
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br In a Comment February we argued that
2019-06-06

In a Comment (February, 2017), we argued that action on the conditions currently referred to as non-communicable diseases (NCDs) may be hampered by the inadequacy of their label. We received a remarkable amount of feedback on this suggestion, and in this Comment we synthesise the responses garnere
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Most infants in NICUs are hospitalized continuously from bir
2019-06-06

Most infants in NICUs are hospitalized continuously from birth, and MRSA infections are largely considered to be horizontally transmitted. Various studies had reported that viable MRSA can be found on the hands of up to 17% of healthcare workers, and on 59% of the environmental surfaces in rooms of
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br Conflict of interest br Case presentation A year old
2019-06-06

Conflict of interest Case presentation A 64-year-old female presented to the emergency room with persistent dizziness that began early that morning. She had a 30-year history of palpitations and known electrocardiogram (ECG) abnormalities. Her pulse was irregular at 130–270min−1 and blood pres
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The standard therapy for chordoma is
2019-06-06

The standard therapy for chordoma is excision. Local recurrence, but not metastasis, is a major determinant of prognosis. Because local recurrence is related to initial surgical margin and intra-operative tumor cell contamination, achieving a safe margin is very important. Boriani [6] reported 153 c
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En Por qu construir un pueblo es la tarea de
2019-06-06

En “\"Por qué construir un pueblo es la tarea de la política radical?”, Laclau profundiza una tensión en su teoría en el marco de la respuesta mek inhibitor Slavoj zžek. Por un lado, la formalidad de la lógica populista, en principio, impide predicar sus alcances en cuanto a la democracia (tanto en
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